Minimizing Multiples

Dr. Conaghan's picture
May 24, 2017

PFC has been a pioneer in enabling patients to have just a single embryo transferred at a time, through the use of genetic testing and freezing of embryos for later use.  At PFC we elect to transfer one embryo in over 90% of patients and our twin rate is 6%. Nationally, clinics perform elective single embryo transfer in less than 30% of patients.  North America has consistently had the highest multiple pregnancy rates in the world but this is changing and should continue to change with the new guidelines for number of embryos to transfer.

The numbers tell the tale: Transferring a single embryo has become a big success story (but we already knew that—and you probably did too).

Dr. Chenette's picture
February 17, 2017

The recent news of several celebrity pregnancies with multiples has caused a lot of talk in the recent press. Beyonce announced she and Jay Z are expecting twins, George and Amal Clooney are expecting twins, and Pharrell and his wife recently welcomed triplets.

PFC’s Dr. Philip Chenette was interviewed by Women’s Health about the recent news. “Carrying a baby one at a time, a singleton pregnancy, is far safer for both mother and baby,” said Dr. Chenette.

You can read the full online article here.

PFC Team's picture
October 11, 2016

The New York Times reports, “The rate of I.V.F. pregnancies that resulted in multiple births dropped to 22 percent in 2014 from 50 percent in 2009.” This is outstanding news to Pacific Fertility Center who has been a big proponent of elective single embryo transfer (eSET) for many years!

The American College of Obstetrics and Gynecology also released an advisory in August stating, “‘electively’ transferring just one embryo at a time can achieve high pregnancy rates with less risk to babies and mothers and ‘a drastic reduction in multi-fetal pregnancy.’” This closely aligns with our moto here at PFC of building families one healthy baby at a time.

Read the full article:

Dr. Chenette's picture
March 14, 2016

Building healthy families, one baby at a time. That’s how we define good fertility care at Pacific Fertility Center.

Multiple gestation—twins, triplets, or more—increases more than just the number of babies. It also increases risks to both baby and mother. Multiples increase the risk of miscarriage, early delivery, and low birth weight. Multiples have a higher risk of cerebral palsy, seizure disorders, birth defects, and cognitive challenges, leading to more problems in school. Mothers of multiples are also more likely to contend with more problems during pregnancy—some potentially serious, such as an increase in diabetes and high blood pressure. They may also experience more problems after delivery, both medical and psychological.

However, a variety of technologies have improved reliability, consistency, and pregnancy rates and reduced the number of embryos transferred. These include:

PFC Team's picture
March 11, 2016

San Francisco, CA – March 11, 2016 – Providing new data on the hazards of transferring two or more embryos after IVF, researchers at Pacific Fertility Center (PFC) report that transferring two or more embryos results in a high rate of multiple gestation with a significant increase in the risk of preterm delivery.

PFC physician and lead author Liyun Li, MD, will present the research findings on today at 6:00 pm at the 2016 Annual Meeting of the Pacific Coast Reproductive Society (PCRS) in Rancho Mirage, CA. The abstract is entitled “Supernumerary Frozen Blastocyst Transfers Result in Unacceptable Rates of Multiple Gestation and Preterm Delivery.” Also presenting the paper are PFC physicians Carolyn Givens, MD, and senior author Philip Chenette, MD.